Przedborski S, Jackson-Lewis V, Yokoyama
R, Shibata T, Dawson VL, Dawson TM. Role of neuronal nitric oxide in MPTP
(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-induced dopaminergic neurotoxicity.
Proc Natl Acad Sci USA, 93:4565-4571, 1996.
Kostic V, Jackson-Lewis V, De Bilbao F, Dubois-Dauphin
M, Przedborski S. Bcl-2: Prolonging life in a transgenic mouse model of
familial amyotrophic lateral sclerosis. Science, 277:559-562, 1997.
Ara J, Przedborski S, Naini AB, Jackson-Lewis
V, Trifiletti RR, Horwitz J, Ischiropoulos H. Inactivation of tyrosine
hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(MPTP). Proc Natl Acad Sci USA, 95:7659-7663, 1998.
Liberatore G, Jackson-Lewis V, Vukosavic
S, Mandir AS, Vila M, McAuliffe WJ, Dawson VL, Dawson TM, Przedborski
S. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration
in the MPTP model of Parkinson's disease. Nature Med, 5:1403-1409,
1999.
Mandir AS, Przedborski S, Jackson-Lewis V,
Wang ZQ, Simbulan-Rosenthal M, Smulson ME, Hoffman BE, Guastella DB, Dawson
VL, Dawson TM. Poly (ADP-ribose) polymerase activation mediates MPTP-induced
parkinsonism. Proc Natl Acad Sci USA, 96:5774-5779, 1999.
Pennathur S, Jackson-Lewis V, Przedborski
S, Heinecke JW. Mass spectrometric quantification of 3-nitrotyrosine,
ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3,
6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's
disease. J Biol Chem, 274:34621-34628, 1999.
Vukosavic S, Dubois-Dauphin M, Romero N,
Przedborski S. Bax and Bcl-2 interaction in a transgenic mouse model of
familial amyotrophic lateral sclerosis. J Neurochem, 73:2460-2468,
1999.
Li M, Ona VO, Guegan C, Chen M, Jackson-Lewis
V, Andrews LJ, Olszewski AJ, Stieg PE, Lee JP, Przedborski S, Friedlander
RM. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse
model. Science, 288:335-339, 2000.
Vukosavic S, Stefanis L, Jackson-Lewis V,
Guégan C, Romero N, Chen C, Dubois-Dauphin M, Przedborski S. Delaying
caspase activation by Bcl-2: a clue to disease retardation in a transgenic
mouse model of amyotrophic lateral sclerosis. J Neurosci, 20:9119-9125,
2000.
Guegan C, Vila M, Rosoklija G, Hays AP, Przedborski
S. Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic
lateral sclerosis. J Neurosci, 21:6569-6576, 2001.
Vila M, Jackson-Lewis V, Vukosavic S, Djaldetti
R, Liberatore G, Offen D, Korsmeyer SJ, Przedborski S. Bax ablation prevents
dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine
mouse model of Parkinson's disease. Proc Natl Acad Sci U S A, 98:2837-2842,
2001.
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